๐งฌ Surgical Biopsy (Open Biopsy) – Complete Explanation
A surgical biopsy, also called an open biopsy, is a procedure in which a surgeon makes a small incision in the skin to remove tissue for diagnostic examination. This method is typically recommended when other biopsy techniques—such as fine-needle aspiration or core needle biopsy—do not provide enough information or fail to reach the suspicious area.
A surgical biopsy is considered one of the most accurate methods for diagnosing various medical conditions, including cancer, infections, and inflammatory diseases.
๐ When is a Surgical Biopsy Needed?
Doctors may choose an open biopsy when:
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Needle biopsies are inconclusive
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The suspicious area is located in a hard-to-reach region
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A larger tissue sample is required for accurate diagnosis
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The entire lump or suspicious growth needs to be completely removed
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There is a strong suspicion of cancer
In certain cases, a surgical biopsy can be both diagnostic and therapeutic, meaning the disease is diagnosed and the abnormal tissue is removed at the same time.
✂️ Types of Surgical Biopsies
There are two main types:
1️⃣ Incisional Biopsy
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Only part of the suspicious tissue or tumor is removed.
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Used when the area is too large to remove entirely.
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Helps confirm the diagnosis before planning full treatment.
2️⃣ Excisional Biopsy
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The entire lump, mass, or suspicious area is removed.
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Common for small tumors, cysts, or lymph nodes.
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Provides the most complete tissue sample for examination.
๐ฌ What Happens After Tissue Removal?
Once the tissue is taken out:
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It is preserved in a special solution.
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Sent to a pathology laboratory.
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A pathologist examines it under a microscope.
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Additional tests may be done:
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Immunohistochemistry
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Molecular testing
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Genetic analysis
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These tests help determine:
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If cancer is present
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The type and grade of cancer
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Whether margins are clear (in excisional biopsies)
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Infection or inflammation
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Other structural abnormalities
๐ฅ Procedure Overview
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Performed under local or general anesthesia, depending on the location.
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Usually an outpatient procedure.
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Incision is closed with sutures and a dressing.
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Recovery time varies from a few days to one week.
⚠️ Possible Risks
Though generally safe, risks may include:
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Bleeding
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Infection
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Pain or swelling
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Scarring
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Reaction to anesthesia
These are usually minor and easily managed.
๐งพ Summary
A surgical (open) biopsy is a procedure where tissue is removed through an incision for detailed examination. It is one of the most reliable methods for diagnosing diseases such as cancer when other biopsy techniques are insufficient.
With two main types—incisional (part removed) and excisional (entire lump removed)—it provides valuable information to guide accurate treatment.
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